Molecular featurization hub (100+ featurizers) for ML. Convert SMILES to numerical representations via fingerprints (ECFP, MACCS, MAP4), descriptors (RDKit 2D, Mordred), pretrained models (ChemBERTa, GIN, Graphormer), and pharmacophore features. Scikit-learn compatible transformers with parallelization, caching, and state persistence. For QSAR, virtual screening, similarity search, and deep learning on molecules.

Query Open Targets Platform GraphQL API for target-disease associations, evidence scores, drug-target links, and safety data. Search targets by gene symbol, diseases by EFO ID, retrieve evidence scores from 20+ data sources, drug mechanisms, and tractability assessments. For ChEMBL bioactivity use chembl-database-bioactivity; for clinical trials use clinicaltrials-database-search.

Query RCSB PDB (200K+ experimental structures) via rcsb-api Python SDK. Text, attribute, sequence, and structure similarity search. Fetch metadata via Schema or GraphQL. Download PDB/mmCIF coordinate files. For AlphaFold predicted structures use alphafold-database-access.

Infer, analyze, and visualize intercellular communication from scRNA-seq data using CellChat (R). Pipeline: create CellChat object from Seurat or count matrix → subset CellChatDB ligand-receptor database → identify over-expressed genes per cell group → infer communication probabilities → compute pathway-level signaling → analyze network centrality (senders, receivers, influencers) → visualize with chord diagrams, heatmaps, and bubble plots → compare across conditions. Human and mouse supported. Use liana for a pure-Python equivalent.

Constraint-based reconstruction and analysis (COBRA) of genome-scale metabolic models. FBA, FVA, gene/reaction knockouts, flux sampling, production envelopes, gapfilling, and media optimization. Use for metabolic engineering strain design, essential gene identification, and flux distribution analysis. For kinetic modeling use tellurium; for pathway visualization use Escher.

Product photography for Etsy — composition, lighting, backgrounds, editing, lifestyle shots, 360 views

Shop branding — banner design, logo, brand story, cohesive listing photography, packaging

Master Shopify analytics and reporting. Understand key metrics, build custom reports, track customer behavior, and make data-driven decisions to grow your Shopify store.

DIY product photography — setup, lighting, backgrounds, editing, lifestyle shots, 360 views

Manage stacked PR workflows with Graphite CLI in Graphite-enabled repos only; supports autonomous coordinator/workmux execution.

Builds and edits Simulink, System Composer, Stateflow, and Simscape models. Use when modifying model structure, parameters, ports, connections, or Stateflow chart internals.

Select the right Python charting library (seaborn, matplotlib, graphviz) and produce publication-quality static visualizations. Use when creating charts, plots, graphs, diagrams, heatmaps, visualizations from data, or when choosing between matplotlib/seaborn/graphviz. Also triggers for network diagrams, flowcharts, dependency trees, state machines, and entity-relationship diagrams. For interactive browser-rendered charts or uploaded data exploration, defer to charting-vega-lite instead.

Convert raster images (photos, paintings, illustrations, line art) into SVG vector reproductions. Use when the user uploads an image and asks to reproduce, vectorize, trace, or convert it to SVG. Also use when asked to decompose an image into shapes, create an SVG version of a picture, or faithfully reproduce artwork as vector graphics. Handles graphic/line-art inputs (Kandinsky, architectural drawings, ink work) via a compositional pipeline that extracts lines as SVG strokes. Do NOT use for creating original SVG illustrations from text descriptions — only for converting existing raster images.

Build MATLAB apps programmatically using uifigure, uigridlayout, UI components, callbacks, and uihtml for web integration. Use when creating GUIs, dashboards, interactive tools, apps with sliders/buttons/dropdowns, or embedding HTML/JavaScript components.

Harden REST and GraphQL APIs against common attack vectors. Apply when building API endpoints, implementing authentication, handling file uploads, or exposing APIs to external consumers.

Use Fabric CLI for Power BI operations — semantic models, reports, DAX queries, refresh, gateways. Activate when users work with Power BI items, need to refresh datasets, execute DAX, manage reports, or troubleshoot refresh failures.

Create interactive KPI dashboards for construction projects. Track schedule, cost, quality, and safety metrics in real-time.

Apply geographic location factors to CWICR estimates. Adjust costs for regional labor rates, material prices, and market conditions.

Build KPI dashboards for construction projects. Track CPI, SPI, quality, safety metrics in real-time.

IoT-based material tracking for construction sites. Monitor material delivery, storage conditions, usage, and inventory with sensors, RFID, GPS, and real-time dashboards.

Analyze git repositories to build security ownership topology, compute bus factor for sensitive code, detect orphaned security-critical files, and export ownership graphs for visualization.

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Operate and maintain the local MCP server for this project. Use when creating MCP host config, troubleshooting tool connectivity, modifying tool domains, or adjusting safety policy flags.

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Complete Birdeye API integration for real-time DeFi data across Solana and 15 other chains. Use for token prices, OHLCV charts, market discovery, on-chain trader intelligence, holder analysis, wallet portfolio & P&L, and WebSocket streams for live prices and whale alerts.

Analyze Solana wallets and multichain portfolios with Zerion API. Use for Solana portfolio value, token positions, transaction history, wallet charts, and PnL. Prefer direct REST API integration, with hosted MCP and x402 on Solana as no-key alternatives for agent workflows.

Extract text from Microsoft Word documents

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> Art direction framework for generating warm minimalist photography via AI image generators (Flux, Midjourney, DALL-E). Separates compositional minimalism from emotional minimalism to avoid the "beau

Design and maintain customer health scoring systems with automated alerts and trending analysis

Build and apply lead scoring models combining firmographic fit, behavioral signals, and intent data for sales prioritization

Create actionable buyer personas using Adele Revella's 5 Rings of Buying Insight methodology—based on real buyer stories, not demographics. Use when: **Understand why buyers buy** (or don't buy) your solution; **Create personas that drive action** rather than gather dust; **Align marketing and sales** around real buyer insights; **Develop messaging** that resonates with actual decision-makers; **Map content** to the buyer's journey

> Understand why customers really buy by uncovering the "job" they're hiring your product to do

Gather the following before selecting channels:

- **Browser tools** for App Store browsing and research

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I am a real-time systems architect who has built chat systems, collaborative

Proposes secure remediation strategies for detected security vulnerabilities including buffer overflows, injection risks, insecure deserialization, improper authentication, and unsafe cryptographic usage. Provides recommended security checks, safer API alternatives, design-level changes, code examples, trade-off analysis, and prioritized remediation plans. Does NOT automatically modify code unless explicitly requested.

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Standard collaboration patterns for all squad agents — worktree awareness, decisions, cross-agent communication

Defensive CI/CD patterns: semver validation, token checks, retry logic, draft detection — earned from v0.8.22

Synthesised view of account health and activity for managers overseeing customer-facing teams (Sales, CS, Professional Services, Presales). Scans project channels, email threads, and Notion pages to surface status, risks, and upcoming milestones, without requiring the manager to trawl through individual channels. Supports proactive account management.

Create videos with Vue using Pellicule - a Vue-native video rendering library

Virtual office dashboard — pixel-art NPCs for your OpenClaw agents. Install, manage, and interact with your retro AI office.

Designs scalable backend architectures covering microservices, event-driven systems, API gateways, and data stores. Use when designing a backend system or when the user mentions backend architecture, scalability, or distributed systems.