Batch extracts and verifies structured information (PMID, title, abstract, methodology, results, etc.) from clinical research literature using PMIDs. Use when the user wants to extract details from specific PMIDs.

Query the ClinicalTrials.gov API v2 to search for clinical trials, retrieve detailed study protocols, and analyze recruitment status; use when you need to find trials by condition/drug, export results, or verify study details by NCT ID.

Access the ENCODE Project REST API to search for and retrieve biological data (biosamples, experiments, etc.). Use this skill when the user needs to query ENCODE data, search by keywords, or retrieve specific objects by accession ID.

Query the NCBI Gene database via E-utilities and the NCBI Datasets API; use it when you need to search genes by symbol/ID and retrieve annotations (RefSeq, GO, location, phenotype) for single or batch gene lists.

Search for gene expression DataSets and Profiles in the NCBI GEO database. Use this skill when the user wants to find microarray, RNA-seq, or other genomic data by keywords, organism, author, or specific fields.

Unified CLI/Python interface for querying genomic, proteomic, structure, and expression data across 20+ bioinformatics databases; use when you need fast, scriptable retrieval by gene/protein IDs or keywords.

Query the NHGRI-EBI GWAS Catalog to retrieve SNP–trait associations, study metadata, and (when available) summary statistics when you need evidence for a variant, trait/disease, gene, or genomic region.

Access JASPAR database for transcription factor binding profiles (matrices), collections, and species via REST API. Use when user wants to search for transcription factors, retrieve matrix details (PFM/PWM), infer profiles from protein sequences, or explore JASPAR collections.

Generates a weekly academic literature report based on keywords using PubMed. Use when the user wants to track recent research progress on a specific topic, automatically retrieving, classifying, and summarizing relevant papers from the last 7 days.

Analyzes research hotspots and recommends literature based on a disease or topic. Use when the user wants to identify current research trends, hot topics, or get literature recommendations for a specific medical field or disease.

Access Scite.ai Smart Citations to classify how a paper is cited (supporting, contrasting, mentioning) and assess scientific claims; use it when you need to evaluate a paper’s reliability or its acceptance in the literature.

Venue-specific LaTeX templates, formatting requirements, and submission guidelines for journals, conferences, posters, and grants—use when a target venue imposes strict layout, page limits, anonymization, or agency compliance rules.

Evidence-Based Medicine diagnostic test calculator. Computes sensitivity, specificity, PPV, NPV, likelihood ratios, NNT, and pre/post-test probability from 2x2 contingency table inputs.

Generate renderable, scientific-style SVG graphics directly from natural-language requirements (no image models). Use when users ask for an image/picture/scientific diagram/visualization poster or explicitly request SVG output for web-embeddable vector graphics.

Recommend academic journals based on manuscript topic, abstract, and impact factor expectations. Use when the user wants to find suitable journals for their research manuscript, especially when they provide a topic, abstract, and target Impact Factor.

Search and locate relevant content within a local knowledge base (files, indices, or PageIndex). Use when you need verifiable citations (file + page/paragraph) to support answers from local sources.

A medical assistant tool that transforms complex biochemical laboratory test results into clear, patient-friendly explanations with safety disclaimers and severity flags.

Integrates multiple news sources into a single, cohesive press release using an inverted pyramid structure and AP style. Use when you have raw news content and a topic, and need a professional press release.

Generates a structured reading tweet from an academic paper (PDF, Word, or Text), highlighting specific product advantages. Use when the user wants to turn a document into a social media post or reading summary.

Checks consistency between paper result descriptions and figure legends (text-only) when the input is a PDF-to-Markdown full text containing page breaks (e.g., `## Page XX`) and legend text; outputs a Markdown consistency report and a UTF-8 CSV issue list.

Generate professional slide-deck SVG images (not PPTX/PDF) when users ask to “create slides / slide deck / PPT” and need image outputs.

Generate concise (typically 1–4 pages) patient-centered medical treatment plans in LaTeX/PDF when a clinician needs an actionable plan with SMART goals, evidence-based interventions, monitoring, and HIPAA-aware documentation.

Automated LLM-driven hypothesis generation and testing for tabular datasets; use when you need systematic exploration of empirical patterns (e.g., fraud detection, content analysis) and want to combine literature insights with data-driven hypothesis evaluation.

Structured scientific hypothesis formulation from observations; use when you have experimental observations or preliminary data and need testable hypotheses with predictions, mechanisms, and validation experiments.

This skill provides a standardized, end-to-end process for auditing any agent skill — from structural integrity to live functional performance. It combines two independent veto gates, static analysis

Runs all necessary checks (lint, tests) and pushes to GitHub. Use this as the final safety gate.

Runs unit tests to quickly verify changes during the development loop.

This skill provides guidance for creating effective skills for Claude Code plugins.

Comprehensive understanding of the spec-kit methodology. Constitution-driven feature development with specify, plan, tasks, and implement phases.

This skill should be used only when the user explicitly asks to use `$ralph-specum-cancel`, or explicitly asks Ralph Specum in Codex to stop execution or remove a spec.

This skill should be used only when the user explicitly asks to use `$ralph-specum-feedback`, or explicitly asks Ralph Specum in Codex to draft or submit feedback.

This skill should be used only when the user explicitly asks to use `$ralph-specum-help`, or explicitly asks Ralph Specum in Codex for help or command guidance.

This skill should be used only when the user explicitly asks to use `$ralph-specum-implement`, or explicitly asks Ralph Specum in Codex to run implementation for approved tasks, quick mode, or an explicit continue request.

This skill should be used only when the user explicitly asks to use `$ralph-specum-index`, or explicitly asks Ralph Specum in Codex to generate or refresh index artifacts.

This skill should be used only when the user explicitly asks to use `$ralph-specum-requirements`, or explicitly asks Ralph Specum in Codex to run the requirements phase.

This skill should be used only when the user explicitly asks to use `$ralph-specum-research`, or explicitly asks Ralph Specum in Codex to run the research phase.

This skill should be used only when the user explicitly asks to use `$ralph-specum-start`, or explicitly asks Ralph Specum in Codex to start or resume a spec.

This skill should be used only when the user explicitly asks to use `$ralph-specum-status`, or explicitly asks Ralph Specum in Codex for status or active spec progress.

This skill should be used only when the user explicitly asks to use `$ralph-specum-switch`, or explicitly asks Ralph Specum in Codex to switch the active spec.

This skill should be used only when the user explicitly asks to use `$ralph-specum-tasks`, or explicitly asks Ralph Specum in Codex to run the tasks phase.

This skill should be used only when the user explicitly asks to use `$ralph-specum-triage`, or explicitly asks Ralph Specum in Codex to triage a large effort into multiple specs.

Use only when the user explicitly invokes `$ralph-specum`, requests Ralph Specum in Codex, asks Ralph Specum to handle a named phase, or explicitly requests autonomous or quick mode or continuation without pauses.

This skill should be used when generating spec artifacts (research.md, requirements.md, design.md, tasks.md), formatting agent output, structuring phase results, or when any Ralph agent needs guidance on concise, scannable output formatting. Applies to all Ralph spec phase agents.

This skill should be used when running an interactive interview before a spec phase, gathering requirements through dialogue, asking the user clarifying questions before delegating to a subagent, or when any Ralph phase command (research, requirements, design, tasks) needs adaptive brainstorming dialogue. Covers the 3-phase algorithm (Understand, Propose Approaches, Confirm and Store).

Spec-driven development transforms feature requests into structured specs through sequential phases, then executes them task-by-task.

Shared changelog conventions and formatting rules referenced by /create-changelog and /update-changelog. Not typically invoked directly.

Multi-turn consultation with Codex CLI. Maintains a conversation across multiple turns using session persistence, unlike single-shot `/codex-exec`.

Analyze what changed and generate a comprehensive test plan covering four escalating levels of testing depth.

Decompose a specification file into shells at `.turbo/shells/<spec-slug>-NN-<title>.md`. Each shell represents one unit of work for a separate Claude Code session.

Guide a collaborative discussion to explore a project idea, then synthesize the conversation into a comprehensive specification at `.turbo/specs/<slug>.md`.