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Sistema de estilos de botones consistentes para iqEngi (Cards, CTAs, Formularios)

使用 Chrome DevTools MCP 进行前端页面调试、布局优化、性能诊断及交互验证。

Executes shell scripts in a safe environment.

Applies Shadowrun cyberpunk aesthetic to UI components. Use when building character sheets, creation cards, gear panels, modal dialogs, or any SR-themed interface elements. Combines systematic craft principles with the distinctive visual language of the Sixth World.

state-lifting

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Systematically deconstruct written content into verifiable claims, validate each using search/documentation, and facilitate informed discussion through structured interviewing.

Redis-backed SSE stream management with stream registry, heartbeat monitoring, completion store for terminal events, and automatic orphan cleanup via background guardian process.

Universal planning for technical and non-technical projects. Domains: software implementation, business, personal, creative, academic, events. Capabilities: feature planning, system architecture, goal setting, milestone planning, requirement breakdown, trade-off analysis, resource allocation, risk assessment. Actions: plan, architect, design, evaluate, breakdown, structure projects. Keywords: implementation plan, technical design, architecture, roadmap, project plan, strategy, goal setting, milestones, timeline, action plan, SMART goals, sprint planning, task breakdown, OKRs. Use when: planning features, designing architecture, creating roadmaps, setting goals, organizing projects, breaking down requirements.

**Core Principle:** Orchestrate skills dynamically. Analyze the task, discover available skills, build the right chain, explain the reasoning, execute step-by-step with confirmation.

PRD 驱动的任务调度与技能管理专家。接收完整 PRD/需求文档，负责拆解业务、选择技术栈、路由到合适的专业 Skill，并维护从方案到落地的全流程。

专用于在 GitHub 上搜索现有的开源库、工具、MCP Server 或最佳实践代码。当你想在开始开发前查找是否有“现成的轮子”或参考案例时使用。

[01] META. Сканирует доступные skills, создает план выполнения и идет шаг за шагом с подтверждением каждого этапа. Triggers on complex tasks, multi-step work, or when structured execution is needed.

Current guidance allows tasks to proliferate without clear Epic/UserStory boundaries. We need explicit criteria in SKILL.md.

专注于数据库设计、SQL 优化和迁移策略。

专注于 Node.js 后端开发模式与最佳实践。

Git 版本控制与协作专家，涵盖 GitHub/Gitee 平台操作、Conventional Commits 规范及 PR/MR 最佳实践。

Perform comprehensive **preliminary alignment-level quality control** for ChIP-seq and ATAC-seq BAM files using **samtools**, **Picard**, and **MultiQC**.

Establish clarity before starting work. Use when beginning any significant task, when input is vague or stream-of-consciousness, or when requirements seem unclear. Handles messy voice input efficiently. This is the first system in the 5-system framework.

A personal knowledge base for **building understanding that compounds over time**. Not a note dump - a structured system for capturing knowledge you can actually retrieve and use.

The Twelve-Factor App methodology for building scalable, maintainable cloud-native applications. Use when designing backend services, APIs, microservices, or any software-as-a-service application. Triggers on deployment patterns, configuration management, process architecture, logging, and infrastructure decisions.

This skill identifies novel transcription factor binding motifs in the promoter regions of genes, or directly from genomic regions of interest such as ChIP-seq peaks, ATAC-seq accessible sites, or differentially acessible regions. It employs HOMER (Hypergeometric Optimization of Motif Enrichment) to detect both known and previously uncharacterized sequence motifs enriched within the supplied genomic intervals. Use the skill when you need to uncover sequence motifs enriched or want to know which TFs might regulate the target regions.

This skill should be used when users need to perform known motif enrichment analysis on ChIP-seq, ATAC-seq, or other genomic peak files using HOMER (Hypergeometric Optimization of Motif EnRichment). It identifies enrichment of known transcription factor binding motifs from established databases in genomic regions.

Automatically detect and normalize Hi-C data. Only .cool or .mcool file is supported. All .mcool files are then checked for existing normalization (supports bins/weight only) and balanced if none of the normalizations exist.

Guide for adding new blockchain chains to OneKey. Use when implementing new chain support, adding blockchain protocols, or understanding chain architecture. Triggers on chain, blockchain, protocol, network, coin, token, add chain, new chain.

Adds new WebSocket event subscriptions to OneKey. Use when implementing new socket events, handling server push messages, or adding real-time data subscriptions. Socket, WebSocket, event, subscription, push, real-time.

OneKey monorepo architecture and code organization. Use when understanding project structure, package relationships, import rules, or component organization. Triggers on architecture, structure, packages, imports, hierarchy, dependencies, monorepo, organization.

Coding patterns and best practices for OneKey development. Use when writing React components, handling promises, error handling, or following code conventions. Triggers on react, component, hooks, promise, async, await, error, pattern, convention, typescript.

Interactive guide for integrating new DeFi modules or protocols into OneKey. Use when adding new DeFi features like staking protocols, lending markets, or entirely new DeFi modules. Triggers on DeFi, protocol, integration, Earn, Borrow, staking, lending, supply, borrow, withdraw, repay, claim, new module, Pendle, Aave, Compound.

Feature development guides for OneKey. Use when adding new chains, socket events, notifications, pages, or routes. Covers blockchain integration, WebSocket subscriptions, push notifications, and navigation patterns.

Documents minimum SDK/OS version requirements for all OneKey platforms. Use when checking platform compatibility, understanding deployment targets, verifying version requirements, or when user asks if their device can run the project. Triggers on minimum version, SDK version, API level, deployment target, platform requirements, iOS version, Android version, Chrome version, Electron version, can I run, environment check, device compatibility, check environment.

Use this skill when working with the 1Password CLI (`op` command) for secrets management, retrieving API keys, or injecting secrets into development environments.

Second step in building instruction context for codebase

Status: ACTIVE

This skill performs differential topologically associating domain (TAD) analysis using HiCExplorer's hicDifferentialTAD tool. It compares Hi-C contact matrices between two conditions based on existing TAD definitions to identify significantly altered chromatin domains.

Status: ACTIVE

[21] UNDERSTAND. Deep research workflow for this project using 150% scope (100% core + 50% boundary), evidence-based reasoning, and structured investigation notes. Use when the task requires investigation, root-cause analysis, or mapping unknown areas. Always maintain a research log file that captures findings, hypotheses, and next branches; use web.run when external verification is needed.

This skill provides a complete and streamlined workflow for performing methylation variability and epigenetic heterogeneity analysis from whole-genome bisulfite sequencing (WGBS) data. It is designed for researchers who want to quantify CpG-level variability across biological samples or conditions, identify highly variable CpGs (HVCs), and explore epigenetic heterogeneity.

You are an expert in 2D bin packing and rectangular packing optimization. Your goal is to help pack rectangular items into 2D bins or sheets while minimizing waste, number of bins used, or maximizing

You are an expert in two-dimensional cutting stock problems and rectangular sheet optimization. Your goal is to help minimize material waste and costs when cutting large sheets (steel plates, glass pa

2D game development principles. Sprites, tilemaps, physics, camera.

Creates high-quality content (blog posts, tweets, newsletters, documentation) that matches the user's writing style and voice. Performs web research to find citations and supporting evidence. Use when user requests blog posts, marketing content, newsletters, tweets, or any written content that should sound authentic and be well-researched.

Third step in building instruction context for codebase

Perform peak calling for ChIP-seq or ATAC-seq data using MACS3, with intelligent parameter detection from user feedback. Use it when you want to call peaks for ChIP-seq data or ATAC-seq data.

Prioritize tasks and issues to determine what to work on and in what order. Use after identification, when planning work, or when unsure what to do next. This is the third system in the 5-system framework.

Status: ACTIVE

Status: ACTIVE

Use when working in Blender, Unity 3D, Unreal Engine, Cinema 4D, VR/AR applications, or any three-dimensional animation work.

Protect your SaaS app from common vulnerabilities. Use when building auth, handling user data, or deploying features. Covers authentication, data protection, API security, and OWASP Top 10 for non-technical founders using AI tools.