Extract quantities from BIM/CAD data for cost estimation. Group by type, level, zone. Generate QTO reports.

Generate comprehensive BIM model validation reports. Check data quality, completeness, and compliance with standards.

Generate BIM Verdi UI components and pages following the established design system. Use when building templates, components, or any frontend for bimverdi.no. Enforces enterprise-calm aesthetics and avoids generic AI patterns.

Binance exchange integration. Trade spot, futures, and manage portfolio on the world's largest crypto exchange.

Systematic approach to analyzing compiled binaries, understanding program behavior, and identifying vulnerabilities without source code access

Advanced binary exploitation and mitigation bypass

Initial reconnaissance on binaries including checksec, file analysis, strings, and symbols. First step for any new target.

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Binds enum values to WPF CommandParameter using x:Static markup extension. Use when passing enum types to commands or avoiding string-based command parameter errors.

Annotate CLIP-seq binding sites to genomic features including 3'UTR, 5'UTR, CDS, introns, and ncRNAs. Use when characterizing where an RBP binds in transcripts.

Functional annotation and taxonomy inference from sequence homology.

Assemble genomes/metagenomes and produce assembly QC artifacts.

Perform metagenomic binning, refinement, and QC with completeness/contamination checks.

De novo motif discovery and known motif enrichment analysis using HOMER and MEME-ChIP. Identify transcription factor binding motifs in ChIP-seq, ATAC-seq, or other genomic peak data. Use when finding enriched DNA motifs in peak sequences.

This skill should be used when the user needs to query COSMIC Cancer Gene Census to check if genes are known cancer genes. Triggers include requests to annotate genes with cancer information, check if variants are in cancer genes, or retrieve cancer gene properties from COSMIC database.

Initialize a bioinformatics project scaffold with reproducible environments, schemas, and data cataloging. Use for new projects or repo setup.

Call genes and annotate basic features for prokaryotes, viruses, and eukaryotes.

Evaluates scientific research rigor using systematic frameworks. Assesses methodology, statistics, biases, and evidence quality. Use when reviewing papers, critiquing claims, designing studies, rating evidence strength (GRADE/Cochrane ROB), checking study design, statistical critique, or risk of bias assessment.

Build marker gene alignments and phylogenetic trees.

Designs and scaffolds bioinformatics pipelines using Prefect (Python) with Dask for local/distributed task execution and Nextflow for HPC scheduler-native execution. Use when an agent must choose between Prefect+Dask vs Nextflow, generate runnable project skeletons, or adapt workflows for laptops, workstations, and HPC clusters (e.g., Slurm/PBS) with reproducibility, caching/resume, and resource-aware configuration.

Cluster proteins into orthogroups and derive pangenome matrices.

Ingest, QC, and map reads with reproducible outputs. Use for raw read processing and coverage stats.

Aggregate results, train ML models, and produce reports with validated references.

Structure prediction and structure-based annotation.

Detect, classify, and QC viral contigs.

Generate reproducible bioinformatics/data-science Methods + run documentation from workflow run artifacts (Nextflow/Snakemake/CWL), including a top-of-doc workflow summary, exact executed commands, tool versions, parameters, QC, and outputs.

Set up and execute phylogenetic biogeographic analyses using BioGeoBEARS in R. Use when users request biogeographic reconstruction, ancestral range estimation, or want to analyze species distributions on phylogenies. Handles input file validation, data reformatting, RMarkdown workflow generation, and result visualization.

Use when implementing data analysis pipelines, statistical tests, or bioinformatics workflows in code (Python/R), particularly for genomics, transcriptomics, proteomics, or other -omics data.

Expert-level biology, biotechnology, genetics, bioinformatics, and computational biology

biologist-analyst

Use when evaluating biological relevance, methodological appropriateness, or scientific validity of bioinformatics approaches, or when choosing between analysis methods/software tools.

Comprehensive biology expert from molecular biology to ecology, covering cell biology, genetics, evolution, and physiology

End-to-end biomarker discovery workflow from expression data to validated biomarker panels. Covers feature selection with Boruta/LASSO, classifier training with nested CV, and SHAP interpretation. Use when building and validating diagnostic or prognostic biomarker signatures from omics data.

Update Biome linting rules, formatting configs, and import organization settings. Use when adding new lint rules, customizing code style, or fixing workspace-specific linting issues.

Use when biome configuration including biome.json setup, schema versions, VCS integration, and project organization.

Use when formatting JavaScript/TypeScript code with Biome's fast formatter including patterns, options, and code style management.

Use when applying Biome's linting capabilities, rule categories, and code quality enforcement to JavaScript/TypeScript projects.

Biome linter/formatter setup. Use when configuring Biome as an alternative to ESLint + Prettier.

Biome 2.x linting and formatting patterns. Use when configuring code quality tools, setting up linting rules, formatting code, or integrating with CI/CD. Covers migration from ESLint/Prettier.

Validates jump metrics against physiological norms. Use when analyzing CMJ or drop jump results, discussing RSI values, jump heights, ground contact times, or when metrics seem unusual.

Uses Oura ring data to make energy-aware decisions about scheduling, task prioritization, and recovery recommendations. Understands HRV, sleep quality, readiness scores, and their implications for productivity.

Expert on ROM/BIOS for ES-1841. Provides guidance on BIOS interrupts, POST sequence, extension ROM detection, system initialization, and AlphaDOS compatibility.

Extract paper references and concepts from a LaTeX repository for the bipartite knowledge graph.

Generate thematic, prose-style narrative digests from GitHub activity

Check remote server CPU, memory, and GPU availability via SSH

Unified guidance for using the bipartite reference library CLI. Use when searching for papers, managing the library, or exploring literature via S2/ASTA.

Automate Philippine BIR (Bureau of Internal Revenue) tax form generation and filing. Handles 1601-C (withholding tax), 2550Q (quarterly VAT), 1702-RT/EX (annual income tax), and ATP (Authorization to Print) validation. Ensures 100% compliance with BIR regulations.

Post tweets, read threads, search X/Twitter from the terminal using bird CLI. Use when automating Twitter, posting from scripts, analyzing tweet threads, monitoring mentions, or working with the Twitter/X API without OAuth.