Initialize a bioinformatics project scaffold with reproducible environments, schemas, and data cataloging. Use for new projects or repo setup.

Call genes and annotate basic features for prokaryotes, viruses, and eukaryotes.

Build marker gene alignments and phylogenetic trees.

Designs and scaffolds bioinformatics pipelines using Prefect (Python) with Dask for local/distributed task execution and Nextflow for HPC scheduler-native execution. Use when an agent must choose between Prefect+Dask vs Nextflow, generate runnable project skeletons, or adapt workflows for laptops, workstations, and HPC clusters (e.g., Slurm/PBS) with reproducibility, caching/resume, and resource-aware configuration.

Cluster proteins into orthogroups and derive pangenome matrices.

Ingest, QC, and map reads with reproducible outputs. Use for raw read processing and coverage stats.

Aggregate results, train ML models, and produce reports with validated references.

Detect, classify, and QC viral contigs.

Generate reproducible bioinformatics/data-science Methods + run documentation from workflow run artifacts (Nextflow/Snakemake/CWL), including a top-of-doc workflow summary, exact executed commands, tool versions, parameters, QC, and outputs.

Set up and execute phylogenetic biogeographic analyses using BioGeoBEARS in R. Use when users request biogeographic reconstruction, ancestral range estimation, or want to analyze species distributions on phylogenies. Handles input file validation, data reformatting, RMarkdown workflow generation, and result visualization.

Use when implementing data analysis pipelines, statistical tests, or bioinformatics workflows in code (Python/R), particularly for genomics, transcriptomics, proteomics, or other -omics data.

Orchestrate hypothesis-driven bioinformatics research projects.

Expert-level biology, biotechnology, genetics, bioinformatics, and computational biology

Use when evaluating biological relevance, methodological appropriateness, or scientific validity of bioinformatics approaches, or when choosing between analysis methods/software tools.

Comprehensive biology expert from molecular biology to ecology, covering cell biology, genetics, evolution, and physiology

Update Biome linting rules, formatting configs, and import organization settings. Use when adding new lint rules, customizing code style, or fixing workspace-specific linting issues.

Use when biome configuration including biome.json setup, schema versions, VCS integration, and project organization.

Use when formatting JavaScript/TypeScript code with Biome's fast formatter including patterns, options, and code style management.

Use when applying Biome's linting capabilities, rule categories, and code quality enforcement to JavaScript/TypeScript projects.

Biome 2.x linting and formatting patterns. Use when configuring code quality tools, setting up linting rules, formatting code, or integrating with CI/CD. Covers migration from ESLint/Prettier.

Expert on ROM/BIOS for ES-1841. Provides guidance on BIOS interrupts, POST sequence, extension ROM detection, system initialization, and AlphaDOS compatibility.

Automate Philippine BIR (Bureau of Internal Revenue) tax form generation and filing. Handles 1601-C (withholding tax), 2550Q (quarterly VAT), 1702-RT/EX (annual income tax), and ATP (Authorization to Print) validation. Ensures 100% compliance with BIR regulations.

Comprehensive Bitbucket pipeline automation using direct Node.js API calls. Monitor pipeline status, analyze failures, download logs, and trigger builds. Use this skill when the user asks to check pipeline status, find failing pipelines, download logs, trigger builds, or debug pipeline failures. No MCP approval prompts required - uses Bash tool with node commands.

This skill enables interaction with BitBucket Server REST API for Pull Request management. Use when the user wants to create, review, comment on, merge, list pull requests, read comments, or manage tasks on BitBucket Server.

Create PRs and debug pipeline failures in Bitbucket with Carefeed conventions. Auto-extracts Jira keys from branches, generates PR descriptions, and diagnoses CI failures. Use when user mentions PRs, pipelines, or CI/CD.

Manage repositories, check pipelines, review PRs, and collaborate on Bitbucket

Comprehensive Bitcoin mining knowledge from 7 industry reports covering 2024 market overview, mining economics, operational handbooks, heat reuse strategies, mining glossary, Stratum V2 protocol specifications, and ultimate mining handbook. Use when planning mining operations, analyzing profitability, optimizing energy efficiency, understanding mining terminology, or exploring sustainable mining practices.

Use when implementing Bitcoin wallet features - provides complete architecture for on-chain Bitcoin transactions, UTXO management, address derivation from Nostr keys, and transaction handling with proper security patterns

bitcoin

Bitrix24 REST API via curl. Use this skill to manage CRM (leads, deals, contacts), tasks, and users.

Quantizes LLMs to 8-bit or 4-bit for 50-75% memory reduction with minimal accuracy loss. Use when GPU memory is limited, need to fit larger models, or want faster inference. Supports INT8, NF4, FP4 formats, QLoRA training, and 8-bit optimizers. Works with HuggingFace Transformers.

Manage passwords and credentials via Bitwarden CLI (bw). Use for storing, retrieving, creating, or updating logins, credit cards, secure notes, and identities. Trigger when automating authentication, filling payment forms, or managing secrets programmatically.

Word, Excel, PPT, PDF 등 기업용 문서를 생성하고, 결과를 docs/exports에 저장하며 임시파일을 자동 정리합니다.

Business Development - assign partnership strategy, market expansion, deal structuring, and ecosystem tasks

Use when exploring Bknd's auto-generated API endpoints. Covers REST endpoint patterns, route listing, module base paths, SDK method mapping, admin panel API explorer, and understanding the API structure.

Use when setting up Bknd SDK in a frontend application. Covers Api class initialization, token storage, auth state handling, React integration with BkndBrowserApp and useApp hook, framework-specific setup (Vite, Next.js, standalone), and TypeScript type registration.

Use when setting up a production database for Bknd. Covers SQLite file, LibSQL/Turso, Cloudflare D1, PostgreSQL, Neon, Supabase, and Xata configuration.

Use when deploying a Bknd application to production hosting. Covers Cloudflare Workers/Pages, Node.js/Bun servers, Docker, Vercel, AWS Lambda, and other platforms.

Use when configuring environment variables for Bknd projects. Covers .env files, secrets management, env injection in config, platform-specific variables, and production security.

Use when uploading files to Bknd storage. Covers MediaApi SDK methods (upload, uploadToEntity), REST endpoints, React integration with file inputs, progress tracking with XHR, browser upload patterns, and entity field attachments.

Use when configuring OAuth or social login providers in a Bknd application. Covers Google OAuth, GitHub OAuth, custom OAuth providers, callback URLs, environment variables, and frontend OAuth integration.

Use when preparing a Bknd application for production deployment. Covers security hardening, environment configuration, isProduction flag, JWT settings, Guard enablement, CORS, media storage, and production checklist.

Use when serving uploaded files to users. Covers API-proxied file serving, direct storage URLs (S3/R2/Cloudinary), CDN configuration, public file URLs, caching headers, image optimization with Cloudinary, and serving files in frontend applications.

Use when managing user sessions in a Bknd application. Covers JWT token lifecycle, session persistence, automatic renewal, checking auth state, invalidating sessions, and handling expiration.

Develop with BlaC state management library for React. Use when creating Cubits, using useBloc/useBlocActions hooks, managing state containers, or implementing inter-bloc communication patterns.

Apply Eskil Steenberg's black box architecture principles to build modular, maintainable software. Automatically refactors code into replaceable components, designs system architectures with clean boundaries, and debugs with modular isolation.

**Status**: ✅ Production Ready

**Version**: 1.0.0

blender-toolkit

Blender 3D creation suite for modeling, animation, rendering, compositing, video editing, and game development. Use for 3D modeling, sculpting, animation, shading, rendering, simulation, video editing, and Python scripting.